Description

3,4-Difluorobenzoyl Chloride is a high-purity, reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the benzoyl chloride core, which significantly influences the electronic properties and metabolic stability of final target molecules. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries, where it is used to introduce the 3,4-difluorobenzoyl moiety into complex structures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in manufacturing advanced herbicides, fungicides, and insecticides, where the difluoro-substitution enhances bioactivity and environmental persistence.
• Liquid Crystal & OLED Material Production: Serves as a building block for fluorine-containing aromatic compounds used in electronic display technologies and organic light-emitting diodes.
• Polymer Modification: Employed to introduce fluorinated aromatic groups into polymer chains, altering thermal stability, chemical resistance, and surface properties.
• Custom Synthesis & Contract Research: A vital reagent for research organizations and CDMOs (Contract Development and Manufacturing Organizations) developing novel fluorinated compounds.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments with unique color fastness and spectral properties.

Basic Information

Item	Detail
Product Name	3,4-Difluorobenzoyl Chloride
CAS No.	76903-88-3
Molecular Formula	C7H3ClF2O
Molecular Weight	176.55 g/mol
Synonyms	3,4-Difluorobenzoic acid chloride; 3,4-Difluorobenzoyl chloride; 3,4-Difluorobenzoic acid chloride; Benzoic acid, 3,4-difluoro-, chloride; 3,4-DFBC; 76903-88-3; 3,4-Difluorobenzoylchlorid
EINECS	Contact for details

Quality Control

Our 3,4-Difluorobenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent hydrolysis. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.