Description

Sultamicillin CAS NO 76497-13-7 is a semi-synthetic, orally active prodrug antibiotic that combines ampicillin and sulbactam in a single molecule. This unique structure provides broad-spectrum antibacterial activity by inhibiting bacterial cell wall synthesis while simultaneously protecting against β-lactamase degradation. It is a critical active pharmaceutical ingredient (API) primarily required by pharmaceutical manufacturers for the formulation of effective oral antibiotic therapies. Its use is essential in treating a variety of bacterial infections, offering a convenient and potent therapeutic option.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in the manufacture of oral antibiotic formulations.
• Formulation of tablets, capsules, and oral suspensions for human pharmaceutical use.
• Treatment of upper and lower respiratory tract infections, including bronchitis and pneumonia.
• Management of urinary tract infections (UTIs) and gynecological infections.
• Treatment of skin and soft tissue infections caused by susceptible bacteria.
• Used in veterinary medicine for treating bacterial infections in animals.
• Research and development of new antibiotic combinations and delivery systems.
• Reference standard in analytical laboratories for quality control and method development.

Basic Information

Product Name	Sultamicillin
CAS No.	76497-13-7
Molecular Formula	C25H30N4O9S2
Molecular Weight	594.66 g/mol
Synonyms	Sultamicillin Tosylate; Sultamicillinum; UNII-7P0F86Q8Q5; (2S,5R,6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid - (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide ester; Ampicillin sulbactam ester; SBTPC; CP-49952
EINECS	Contact for details

Quality Control

Our Sultamicillin is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical actives. Each batch is tested against relevant pharmacopeial standards (such as USP/EP) for identity, purity, and potency. Comprehensive testing includes assay, related substances, residual solvents, and microbiological examination. A Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. The original container should be kept tightly sealed after each use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%
Microbial Enumeration	Complies with EP/USP

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.