Description

n-(8-Benzyl-8-Azabicyclo[3.2.1]Oct-3-Yl)-2,3,4-Trimethoxy-Benzamide Hydrochloride is a high-purity, complex organic salt with significant pharmacological research interest. This compound matters as a key advanced pharmaceutical intermediate or reference standard for developing novel therapeutic agents, particularly in the central nervous system domain. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates targeting neurological receptors.
• Medicinal Chemistry Research: Used as a reference compound or starting material for structure-activity relationship (SAR) studies and lead optimization.
• Analytical Reference Standard: Employed in HPLC, LC-MS, or NMR for method development, validation, and quality control of related substances.
• Academic & Institutional Research: Facilitates biochemical and pharmacological studies in university and institutional labs exploring new therapeutic pathways.
• Contract Manufacturing (CMO): Supplied to CMOs for use in custom synthesis and small-scale cGMP production for clinical trial materials.
• Biotech R&D: Utilized in early-stage discovery projects within biotechnology companies focusing on CNS disorders.

Basic Information

Item	Details
Product Name	n-(8-Benzyl-8-Azabicyclo[3.2.1]Oct-3-Yl)-2,3,4-Trimethoxy-Benzamide Hydrochloride
CAS No.	76352-12-0
Molecular Formula	C26H34N2O4·HCl
Molecular Weight	475.02 g/mol (for free base: 438.56 g/mol)
Synonyms	2,3,4-Trimethoxy-N-(8-benzyl-8-azabicyclo[3.2.1]oct-3-yl)benzamide hydrochloride; 8-Benzyl-3-[(2,3,4-trimethoxybenzoyl)amino]-8-azabicyclo[3.2.1]octane hydrochloride; 76352-12-0; Benzamide, N-(8-benzyl-8-azabicyclo[3.2.1]oct-3-yl)-2,3,4-trimethoxy-, hydrochloride; 8-Benzyl-8-azabicyclo[3.2.1]octan-3-amine, N-(2,3,4-trimethoxybenzoyl)-, hydrochloride; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our n-(8-Benzyl-8-Azabicyclo[3.2.1]Oct-3-Yl)-2,3,4-Trimethoxy-Benzamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment aligns with the standards expected for pharmaceutical research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.