Description

8-Deoxyrifamycin W 23-Acetate is a semi-synthetic derivative of the rifamycin class of antibiotics, specifically modified at the 8-position. This compound is of significant interest in pharmaceutical research and development for its role as a key intermediate in synthesizing novel antimicrobial agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of next-generation antibiotics targeting resistant bacterial strains.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced rifamycin analogs and novel antibiotic candidates.
• Antimicrobial Research: Used in biochemical and microbiological studies to investigate structure-activity relationships (SAR) and mechanisms of action against bacteria.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry: Employed in scale-up and optimization studies for the industrial production of rifamycin-based therapeutics.

Basic Information

Product Name	8-Deoxyrifamycin W 23-Acetate
CAS No.	75352-21-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	8-Deoxy-23-O-acetylrifamycin W; Rifamycin W, 8-deoxy-, 23-acetate; 23-Acetyl-8-deoxyrifamycin W; 8-Deoxyrifamycin W acetate; (8S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-11,13,15,17,19-Pentahydroxy-12,16,18-trimethoxy-4,10,22-trimethyl-2-oxo-1-oxacyclodocosa-9,19,21-trien-14-yl acetate (IUPAC); Antibiotic X 5108; Antibiotic X-5108
EINECS	Contact for details

Quality Control

Our 8-Deoxyrifamycin W 23-Acetate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.