Description

8-Deoxy-13-Hydroxyrifamycin W is a key semisynthetic derivative and chemical intermediate in the rifamycin antibiotic family. This compound is valued for its role in the research and development of novel antimicrobial agents targeting resistant bacterial strains. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) for the synthesis of advanced rifamycin-based therapeutics.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of next-generation rifamycin antibiotics and analogs.
• Antimicrobial Research: Used in biochemical and microbiological studies to investigate structure-activity relationships (SAR) against Mycobacterium tuberculosis and other pathogens.
• API Development: Serves as a building block in the manufacturing process of active pharmaceutical ingredients for anti-tuberculosis and anti-Gram-positive bacterial drugs.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Medicinal Chemistry: A valuable scaffold for designing and synthesizing new chemical entities with potential antibacterial, antiviral, or anticancer activity.

Basic Information

Product Name	8-Deoxy-13-Hydroxyrifamycin W
CAS No.	75352-20-4
Molecular Formula	C38H47NO12
Molecular Weight	709.78 g/mol
Synonyms	8-Deoxy-13-hydroxy-rifamycin W; Rifamycin W, 8-deoxy-13-hydroxy-; 13-Hydroxy-8-deoxyrifamycin W; (12E,14E,16E,18S,19E,21S,22R,23S,24E,26S,27S,28E)-22,27-Dihydroxy-5,11,23,29-tetramethoxy-2,4,30-trimethyl-1-oxa-6-azacyclohexatriaconta-3,12,14,16,18,20,24,26,28,30,32-undecaene-7,17-dione
EINECS	Contact for details

Quality Control

Our 8-Deoxy-13-Hydroxyrifamycin W is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to Orange Powder
Identification (IR)	Conforms to Reference Spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH Guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.