Description

8,23-Dideoxy-23-Oxorifamycin W is a key semi-synthetic derivative and chemical intermediate in the rifamycin antibiotic class. This compound is valued for its role in the research and development of novel antimicrobial agents targeting resistant bacterial strains. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) for the synthesis of advanced rifamycin analogs.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel rifamycin-based antibiotics and derivatives.
• Antimicrobial Research: Used in biochemical and microbiological studies to investigate structure-activity relationships (SAR) against Mycobacterium tuberculosis and other pathogens.
• API Development: Serves as a precursor in the development and scale-up processes for new active pharmaceutical ingredients.
• Reference Standard: Employed as a high-purity analytical standard in quality control (QC) and method development for rifamycin-related compounds.
• Medicinal Chemistry: A valuable scaffold for designing and testing new chemical entities with potential antibacterial, antiviral, or anti-cancer properties.

Basic Information

Product Name	8,23-Dideoxy-23-Oxorifamycin W
CAS No.	75352-17-9
Molecular Formula	C38H47NO12
Molecular Weight	709.78 g/mol
Synonyms	23-Deoxy-27-O-demethyl-25-O-deacetylrifamycin W; 23-Deoxy-27-O-demethyl-25-O-deacetyl-rifamycin W; Rifamycin W, 8,23-dideoxy-23-oxo-; 8,23-Dideoxy-23-oxorifamycin W; (12Z,14E,24E)-(2S,12S,13S,14R,15S,16S,17R,18R,19S,20R,21S,22S,26R)-6,9,15,17,19-Pentahydroxy-23-methoxy-2,4,12,14,20,22-hexamethyl-1,7-dioxo-1,2-dihydro-2,7-epoxynaphtho[2,1-b]furan-13-yl acetate
EINECS	Contact for details

Quality Control

Our 8,23-Dideoxy-23-Oxorifamycin W is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (IR, NMR), and residual solvent analysis to ensure it meets high-grade standards suitable for research and pharmaceutical development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.