Description

4-Hydroxyphenoxymethylpenicillin Potassium is a semi-synthetic penicillin derivative, specifically a potassium salt of a hydroxyphenoxymethyl penicillin. This compound is valued for its role as a key intermediate in the synthesis of advanced β-lactam antibiotics, offering a crucial building block for pharmaceutical R&D and production. It is primarily needed by manufacturers and research institutions in the pharmaceutical industry focused on developing and producing novel antibacterial agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of specialized penicillin and β-lactam antibiotic derivatives.
• Antibacterial Agent Research: Used in research and development to study structure-activity relationships and create new antibiotic compounds with potentially improved efficacy or spectrum.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the multi-step manufacturing process of specific penicillin-based APIs.
• Biochemical Research: Utilized in laboratory studies investigating bacterial resistance mechanisms and the mode of action of β-lactam antibiotics.
• Reference Standard: Can be used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	4-Hydroxyphenoxymethylpenicillin Potassium
CAS No.	75319-62-9
Molecular Formula	C₁₇H₁₉KN₂O₆S
Molecular Weight	418.51 g/mol
Synonyms	Potassium 4-Hydroxyphenoxymethylpenicillinate; 4-Hydroxyphenoxymethylpenicillin Potassium Salt; Penicillin V, 4'-hydroxy-, potassium salt; 4-Hydroxyphenoxymethylpenicillin K; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(4-hydroxyphenoxy)acetamido]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid potassium salt
EINECS	Contact for details

Quality Control

Our 4-Hydroxyphenoxymethylpenicillin Potassium is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from tests such as HPLC assay, related substances, water content, and residual solvents. Our quality standards are designed to meet the rigorous demands of pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Recommended long-term storage temperature is 2-8°C (refrigerated). Allow the container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Potassium Content	9.0% - 10.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.