Description

Dansyl Glutathione is a fluorescently labeled derivative of the essential tripeptide antioxidant glutathione. This compound is a critical research tool, enabling the sensitive detection, quantification, and study of glutathione and its related metabolic pathways. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and life science sectors for advanced analytical applications.

Application

• Biochemical Research: As a fluorescent probe for studying glutathione metabolism, redox status, and enzyme kinetics (e.g., glutathione S-transferase activity).
• Analytical Chemistry: Serving as a high-sensitivity internal standard or derivatization agent for the HPLC or LC-MS analysis of glutathione and other thiols.
• Pharmaceutical Development: Used in assay development for drug discovery programs targeting oxidative stress and detoxification pathways.
• Diagnostic Reagent Manufacturing: A key component in the formulation of diagnostic kits for measuring glutathione levels in clinical and research samples.
• Cell Biology Studies: Employed in fluorescence microscopy and flow cytometry to visualize and measure intracellular glutathione concentrations.

Basic Information

Product Name	Dansyl Glutathione
CAS No.	75017-02-6
Molecular Formula	C₂₀H₃₀N₄O₉S
Molecular Weight	502.54 g/mol
Synonyms	N-Dansylglutathione; DNS-Glutathione; 5-(Dimethylamino)naphthalene-1-sulfonyl glutathione; L-γ-Glutamyl-L-cysteinylglycine dansyl adduct; Glutathione dansyl derivative; Glutathione-DNS; GS-DNS; N-(1-Dimethylaminonaphthalene-5-sulfonyl)glutathione
EINECS	Contact for details

Quality Control

Our Dansyl Glutathione is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and diagnostic applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. The product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions should be avoided to maintain stability and performance.

Specification

Item	Specification
Appearance	Yellow to light brown powder or solid
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.