Description

n-(3,5-Dinitrobenzoyl)-DL-Leucine is a specialized chiral derivatizing agent and synthetic intermediate of high purity. This compound is critical for the resolution and analytical determination of enantiomers, particularly in pharmaceutical research and development. It is primarily utilized by analytical laboratories, R&D chemists, and manufacturers in the pharmaceutical and fine chemical sectors for chiral chromatography and asymmetric synthesis.

Application

• Chiral Derivatizing Agent (CDA): Used to convert enantiomeric mixtures into diastereomers for separation and analysis via HPLC or other chromatographic methods.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Employed as a high-purity standard for method development and validation in chiral analytical laboratories.
• Research & Development: Essential tool in academic and industrial research focused on stereochemistry, asymmetric catalysis, and drug discovery.
• Quality Control: Used in the QC testing of chiral drugs to ensure enantiomeric purity and regulatory compliance.

Basic Information

Product Name	n-(3,5-Dinitrobenzoyl)-DL-Leucine
CAS No.	74928-54-4
Molecular Formula	C13H15N3O7
Molecular Weight	325.28 g/mol
Synonyms	DNB-Leucine; (RS)-2-[(3,5-Dinitrobenzoyl)amino]-4-methylpentanoic acid; DL-Leucine, N-(3,5-dinitrobenzoyl)-; N-(3,5-Dinitrobenzoyl)leucine; 3,5-Dinitrobenzoyl-DL-leucine; DNB-DL-Leu; (DL)-N-(3,5-Dinitrobenzoyl)leucine
EINECS	Contact for details

Quality Control

Our n-(3,5-Dinitrobenzoyl)-DL-Leucine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and analytical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.