Description

3,5-Difluoro-4-Hydroxybenzoic Acid is a fluorinated aromatic carboxylic acid derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both phenolic and carboxylic acid functional groups on a difluorinated benzene ring, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators, where the fluorine atoms enhance biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing monomers and polymers used in advanced display technologies and organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated into polymer backbones to impart specific characteristics such as improved thermal stability, chemical resistance, or unique optical properties.
• Chemical Research & Development: A valuable reagent in medicinal chemistry and material science labs for structure-activity relationship (SAR) studies and the creation of compound libraries.
• Coordination Chemistry: Can act as a ligand for metal complexes in catalytic applications or as a component in metal-organic frameworks (MOFs).

Basic Information

Product Name	3,5-Difluoro-4-Hydroxybenzoic Acid
CAS No.	74799-63-6
Molecular Formula	C7H4F2O3
Molecular Weight	174.10 g/mol
Synonyms	4-Hydroxy-3,5-difluorobenzoic Acid; 3,5-Difluoro-4-hydroxybenzoic acid; Benzoic acid, 3,5-difluoro-4-hydroxy-; 3,5-Difluoro-4-hydroxy-benzoic acid; 3,5-Difluoro-4-hydroxybenzoicacid; 3,5-Difluoro-4-hydroxy-benzoicacid; 4-Hydroxy-3,5-difluorobenzoicacid
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-Hydroxybenzoic Acid is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent absorption of moisture from the atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	215 - 220 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.