Description

1,4-Di(7-Guanosyl)Butane is a specialized nucleoside derivative with a unique linker structure, offering significant value in advanced biochemical research and pharmaceutical development. Its primary importance lies in its role as a sophisticated building block for oligonucleotide synthesis and as a potential precursor for novel antiviral or anticancer agents. This high-purity compound is essential for research institutions, pharmaceutical R&D departments, and biotechnology companies focused on nucleic acid chemistry, prodrug design, and targeted therapeutic development.

Application

• Oligonucleotide Synthesis: Serves as a modified nucleoside phosphoramidite precursor for constructing specialized DNA/RNA sequences with enhanced stability or binding properties.
• Antiviral Research: Investigated as a potential prodrug or intermediate in the development of nucleoside analog therapeutics targeting viral polymerases.
• Biochemical Probes: Used in the design of fluorescent or affinity-tagged nucleotide probes for studying enzyme mechanisms and nucleic acid interactions.
• Pharmaceutical Intermediate: Acts as a key synthetic intermediate for novel therapeutic candidates in oncology and virology pipelines.
• Academic Research: Employed in university and institutional labs for fundamental studies on nucleic acid structure, function, and metabolism.
• Diagnostic Development: Potential use in creating components for molecular diagnostic assays and biosensors.

Basic Information

Product Name	1,4-Di(7-Guanosyl)Butane
CAS No.	74746-58-0
Molecular Formula	C₁₉H₂₆N₁₀O₈
Molecular Weight	522.48 g/mol
Synonyms	1,4-Bis(7-guanosinyl)butane; N²,2'-O-Diguanosin-7-yl-1,4-diaminobutane; 1,4-Di(N²,2'-O-diguanosin-7-yl)butane; 1,4-Di(7-deazaguanosin-7-yl)butane (common name); Bis(7-guanosyl)butane; 1,4-Bis(7-deazaguanosin-7-yl)butane; G(7)-C4-G(7) linker; 7-Deazaguanosine butane linker dimer
EINECS	Contact for details

Quality Control

Our 1,4-Di(7-Guanosyl)Butane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.