Description

2-Chloro-3-(4-Fluorophenyl)-3-Oxopropanoic Acid is a high-purity, specialized organic building block of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is essential for research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in the synthesis of novel fluorinated compounds and heterocyclic systems.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated drug candidates, including potential kinase inhibitors and anti-inflammatory agents.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging the bioactivity of the fluorophenyl moiety.
• Fine Chemical Synthesis: Serves as a versatile precursor for producing more complex esters, amides, and heterocyclic compounds like pyrazoles and isoxazoles.
• Material Science: Potential building block for specialty polymers and advanced organic materials requiring specific fluorinated components.
• Academic & R&D: Utilized in methodological studies and as a reference standard in organic chemistry research focused on fluorination and carbonyl chemistry.

Basic Information

Product Name	2-Chloro-3-(4-Fluorophenyl)-3-Oxopropanoic Acid
CAS No.	74476-70-3
Molecular Formula	C9H6ClFO3
Molecular Weight	216.59 g/mol
Synonyms	2-Chloro-3-(4-fluorophenyl)-3-oxopropanoic acid; 3-Oxo-2-chloro-3-(4-fluorophenyl)propanoic acid; 4-Fluorobenzoylacetic acid chloride (tautomer); 2-Chloro-3-(p-fluorophenyl)-3-oxopropionic acid; (4-Fluorobenzoyl)chloroacetic acid; α-Chloro-4-fluorobenzoylformic acid; 74476-70-3; Propanoic acid, 2-chloro-3-(4-fluorophenyl)-3-oxo-
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-3-(4-Fluorophenyl)-3-Oxopropanoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.