Description

2'-Deoxyguanosine 5'-(Tetrasodium Triphosphate) is a high-purity nucleotide derivative essential for biochemical and pharmaceutical research. This compound serves as a critical building block and substrate in enzymatic reactions, particularly those involving DNA polymerases and kinases. It is primarily utilized by researchers and manufacturers in the fields of molecular biology, diagnostics, and oligonucleotide synthesis.

Application

• Oligonucleotide Synthesis: A key monomer (dGTP) for the enzymatic or solid-phase synthesis of DNA strands and probes.
• PCR & Molecular Diagnostics: Used as a substrate for DNA polymerases in polymerase chain reaction (PCR), qPCR, and sequencing applications.
• Enzymology Studies: Serves as a phosphate donor or substrate in kinase and polymerase activity assays and mechanistic studies.
• Biochemical Research: Fundamental reagent for studying DNA replication, repair mechanisms, and nucleic acid metabolism.
• Pharmaceutical Development: Potential raw material or intermediate in the development of antiviral or anticancer nucleotide analogs.
• Diagnostic Kit Manufacturing: Component in master mixes and kits for clinical diagnostics and genetic testing.

Basic Information

Product Name	2'-Deoxyguanosine 5'-(Tetrasodium Triphosphate)
CAS No.	74299-51-7
Molecular Formula	C10H12N5Na4O13P3
Molecular Weight	629.10 g/mol (anhydrous)
Synonyms	dGTP, Tetrasodium salt; 2'-Deoxyguanosine-5'-triphosphate tetrasodium salt; Deoxyguanosine triphosphate tetrasodium salt; dGTP-Na4; 5'-dGTP; 2'-Deoxy-GTP; Guanosine, 2'-deoxy-, 5'-(tetrahydrogen triphosphate), tetrasodium salt
EINECS	Contact for details

Quality Control

Our 2'-Deoxyguanosine 5'-(Tetrasodium Triphosphate) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure high purity, identity, and consistency, suitable for sensitive research and in-vitro diagnostic applications. Certificates of Analysis (COA) with detailed HPLC purity data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term storage, desiccate at -20°C. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95% (Anhydrous basis)
Purity (HPLC, anhydrous)	≥ 98%
Water Content (KF)	≤ 5.0 %
pH (1% Solution)	6.0 - 8.0
Endotoxin (LAL)	< 10 EU/mg (if specified)
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.