Description

Atropine β-(n-Methylpiperazinyl)Propionate is a specialized synthetic derivative of the tropane alkaloid atropine, designed for advanced pharmaceutical research and development. This compound is significant for its potential to modulate muscarinic acetylcholine receptor activity with modified pharmacokinetic properties. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in the fields of neurology, ophthalmology, and anesthesiology.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel anticholinergic and antispasmodic drug candidates.
• Biochemical Research: Used as a reference standard or active agent in studies investigating muscarinic receptor subtypes and signal transduction pathways.
• Preclinical Development: Employed in animal model studies to evaluate the efficacy, toxicity, and metabolic profile of new chemical entities targeting the parasympathetic nervous system.
• Analytical Standard: Provides a high-purity compound for use in method development and validation in quality control laboratories (HPLC, GC-MS).
• Academic Research: Utilized in university and institutional labs for fundamental pharmacological and medicinal chemistry research.

Basic Information

Product Name	Atropine β-(n-Methylpiperazinyl)Propionate
CAS No.	74191-76-7
Molecular Formula	C22H33N3O3
Molecular Weight	387.52 g/mol
Synonyms	Atropine N-Methylpiperazine Propionate; 8-Azabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenylpropanoate 2-(4-methylpiperazin-1-yl)ethyl ester; Tropine tropate β-(N-methylpiperazinyl) propionate; (1R,3r,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenylpropanoate 2-(4-methylpiperazin-1-yl)ethyl ester
EINECS	Contact for details

Quality Control

Our Atropine β-(n-Methylpiperazinyl)Propionate is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We adhere to high standards suitable for research and development purposes. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.