Description

1,N(6)-Etheno-2-Azaadenosine Guanosine 3'-Phosphodiester is a chemically modified nucleoside phosphodiester, a sophisticated building block in nucleic acid chemistry. This compound is valued for its role in the synthesis of structurally unique oligonucleotides and as a critical research tool for studying nucleic acid structure, function, and interactions. It is primarily utilized by research institutions and biotechnology companies focused on advanced molecular biology, medicinal chemistry, and the development of novel diagnostic or therapeutic agents.

Application

• Oligonucleotide Synthesis: A key intermediate for constructing modified DNA/RNA strands with enhanced stability or specific binding properties.
• Biochemical Research: Used as a probe or substrate in enzymatic studies to investigate polymerase activity, repair mechanisms, and nucleic acid metabolism.
• Medicinal Chemistry: Serves as a precursor in the development of nucleotide-based therapeutics, including potential antivirals or gene-silencing agents.
• Structural Biology: Employed to introduce specific modifications for X-ray crystallography or NMR studies of nucleic acid-protein complexes.
• Diagnostic Assay Development: Can be incorporated into probes for high-sensitivity detection systems, such as qPCR or fluorescence in situ hybridization (FISH).

Basic Information

Item	Detail
Product Name	1,N(6)-Etheno-2-Azaadenosine Guanosine 3'-Phosphodiester
CAS No.	73962-09-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1,N6-Etheno-2-azaadenosine guanosine 3'-phosphodiester; 2-Aza-1,N6-ethenoadenosine guanosine 3'-phosphodiester; ε-2-Azaadenosine guanosine 3'-phosphodiester; Modified nucleoside phosphodiester; 73962-09-1; Azaethenoadenosine-guanosine dimer
EINECS	Contact for details

Quality Control

Every batch of 1,N(6)-Etheno-2-Azaadenosine Guanosine 3'-Phosphodiester is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (e.g., by MS, NMR), and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term stability, consider storage at -20°C under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.