Description

Leukotriene C4 Methyl Ester is a chemically modified derivative of the potent inflammatory mediator leukotriene C4. This compound is a critical reference standard and research tool for studying the biochemical pathways and physiological roles of cysteinyl leukotrienes. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in immunology, respiratory disease, and inflammation research.

Application

• Biochemical Research: Used as a key reference standard in the study of leukotriene biosynthesis, metabolism, and receptor interactions.
• Pharmaceutical Development: Serves as a critical intermediate or analytical standard in the discovery and development of drugs targeting asthma, allergies, and inflammatory conditions.
• Analytical Chemistry: Employed as a high-purity calibrant in LC-MS, HPLC, and other chromatographic methods for quantitative analysis of leukotriene pathways.
• Enzyme Inhibition Studies: Utilized in assays to evaluate the efficacy of potential inhibitors of enzymes like leukotriene C4 synthase.
• Cell Signaling Research: Applied in vitro to investigate the role of cysteinyl leukotrienes in cellular signaling cascades and inflammatory responses.

Basic Information

Product Name	Leukotriene C4 Methyl Ester
CAS No.	73958-10-8
Molecular Formula	C₂₆H₄₁N₃O₇S
Molecular Weight	539.69 g/mol
Synonyms	LTC4 Methyl Ester; 5(S)-Hydroxy-6(R)-S-glutathionyl-7,9-trans-11,14-cis-eicosatetraenoic Acid Methyl Ester; Methyl (5S,6R)-6-[(2S)-2-Amino-2-carboxyethyl]sulfanyl-5-hydroxyicosa-7,9,11,14-tetraenoate; NSC 339529; Leukotriene C4 Me ester
EINECS	Contact for details

Quality Control

Our Leukotriene C4 Methyl Ester is produced under stringent conditions to ensure high chemical purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC purity analysis and structural confirmation (NMR, MS). A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Solubility	Soluble in ethanol, DMSO; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.