Description

1-(2-Carboxyethyl)Deoxyadenosine 5'-Monophosphate is a chemically modified nucleotide monophosphate derivative, serving as a critical building block and research reagent in advanced biochemical applications. Its value lies in its role as a versatile intermediate for the synthesis of modified oligonucleotides and probes, enabling precise genetic and enzymatic studies. This high-purity compound is essential for researchers and manufacturers in the fields of pharmaceutical development, molecular diagnostics, and academic research, where reliable and well-characterized nucleotide analogs are paramount.

Application

• Oligonucleotide Synthesis: A key phosphoramidite precursor for introducing specific modifications into synthetic DNA and RNA strands.
• Enzyme Substrate & Inhibitor Studies: Used to investigate the activity and kinetics of nucleotidyltransferases, polymerases, and other nucleotide-processing enzymes.
• Probe Development: Acts as a component in the creation of labeled nucleotide probes for hybridization assays and diagnostic applications.
• Biochemical Research: Employed in studying DNA repair mechanisms, epigenetic modifications, and signal transduction pathways involving nucleotides.
• Pharmaceutical Intermediate: Serves as a specialized intermediate in the research and development of novel antiviral or anticancer nucleotide analog therapeutics.

Basic Information

Product Name	1-(2-Carboxyethyl)Deoxyadenosine 5'-Monophosphate
CAS No.	73095-00-8
Molecular Formula	C13H18N5O8P
Molecular Weight	403.28 g/mol
Synonyms	1-(2-Carboxyethyl)-2'-deoxyadenosine 5'-monophosphate; 1-Carboxyethyldeoxyadenosine monophosphate; 1-(2-Carboxyethyl)-dAMP; N1-(2-Carboxyethyl)-2'-deoxyadenosine-5'-monophosphate; 2'-Deoxy-N1-(2-carboxyethyl)adenosine 5'-monophosphate; 5'-dAMP-CE; dAMP-CE; 1-CE-dAMP
EINECS	Contact for details

Quality Control

Our production of 1-(2-Carboxyethyl)Deoxyadenosine 5'-Monophosphate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting compliance in research and cGMP-grade manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.