Description

Octadeoxyriboadenylic Acid CAS NO 72673-13-3 is a synthetic oligonucleotide composed of eighteen deoxyadenosine monophosphate units. This compound is a critical tool in molecular biology and biochemistry research, serving as a fundamental building block for studying nucleic acid interactions and enzyme mechanisms. It is primarily utilized by research institutions, diagnostic kit manufacturers, and biotechnology companies engaged in genetic analysis, probe development, and therapeutic oligonucleotide synthesis.

Application

• Primer and Probe Synthesis: Used as a long homopolymeric primer or probe in polymerase chain reaction (PCR), sequencing, and hybridization assays.
• Molecular Biology Research: Serves as a model substrate for studying the kinetics and specificity of DNA polymerases, nucleases, and other DNA-modifying enzymes.
• Diagnostic Development: Acts as a key component in the design and manufacture of diagnostic kits for genetic testing and pathogen detection.
• Therapeutic Oligonucleotide Precursor: Functions as a starting material or intermediate in the synthesis of antisense oligonucleotides and other nucleic acid-based therapeutics.
• Biophysical Studies: Employed in studies investigating DNA structure, stability, and hybridization properties due to its defined length and sequence.
• Quality Control Standard: Used as a reference standard in analytical laboratories to calibrate instruments and validate methods for oligonucleotide analysis.

Basic Information

Product Name	Octadeoxyriboadenylic Acid
CAS No.	72673-13-3
Molecular Formula	C180H225N90O108P18
Molecular Weight	~5580.6 g/mol (for free acid)
Synonyms	dA18; Poly(dA)18; Oligodeoxyadenylic acid 18-mer; 18-mer deoxyadenosine oligonucleotide; Deoxyadenosine oligonucleotide (18 units); Polydeoxyadenylic acid (n=18); Homopolymeric dA18; DNA oligonucleotide d(A)18
EINECS	Contact for details

Quality Control

Our Octadeoxyriboadenylic Acid is manufactured under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot is characterized by advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid or lyophilized powder
Identification (HPLC/MS)	Conforms to reference
Purity (HPLC)	≥ 95%
Molecular Weight Verification (MS)	Conforms to theoretical mass
Water Content (KF)	≤ 5.0%
Endotoxin	< 10 EU/mg (if specified)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.