Description

5-(4-Fluorophenyl)-1,2,4-Oxadiazole-3-Carboxylic Acid is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique oxadiazole core and fluorine substituent impart desirable biological activity and metabolic stability. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the oxadiazole moiety.
• Material Science: Serves as a building block for specialty polymers and liquid crystals, where the fluorine atom can enhance thermal stability and optical properties.
• Chemical Biology Probe: Employed in the design of molecular probes and enzyme inhibitors for biochemical and pharmacological research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring fluorinated heterocycles.

Basic Information

Product Name	5-(4-Fluorophenyl)-1,2,4-Oxadiazole-3-Carboxylic Acid
CAS No.	72542-80-4
Molecular Formula	C9H5FN2O3
Molecular Weight	208.15 g/mol
Synonyms	5-(4-Fluorophenyl)-1,2,4-oxadiazole-3-carboxylic acid; 3-Carboxy-5-(4-fluorophenyl)-1,2,4-oxadiazole; 4-Fluorophenyl-1,2,4-oxadiazole-3-carboxylic acid; 1,2,4-Oxadiazole-3-carboxylic acid, 5-(4-fluorophenyl)-; FPOA; 72542-80-4 (CAS)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development use. Every batch is characterized using modern analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for each parameter are available upon request, providing full traceability and supporting your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.