Description

Poly(2-Fluoroadenylic Acid) is a synthetic, fluorinated derivative of adenylic acid, a key nucleotide building block. This modification introduces a fluorine atom at the 2-position of the adenine ring, significantly altering its biochemical properties and resistance to enzymatic degradation. It is primarily utilized in advanced biochemical research and pharmaceutical development, particularly in the study of nucleic acid interactions, enzyme mechanisms, and as a potential precursor for novel therapeutic agents. The product is supplied as a high-purity material suitable for sensitive applications.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving adenosine deaminase and other nucleotide-processing enzymes.
• Nucleic Acid Chemistry: Serves as a modified nucleotide monomer for the synthesis of oligonucleotides with enhanced stability for diagnostic probes or aptamers.
• Pharmaceutical Intermediates: Acts as a key synthetic intermediate in the development of antiviral or anticancer nucleoside analog drugs.
• Mechanistic Studies: Employed to investigate the role of specific functional groups in nucleotide recognition and binding within biological systems.
• Reference Standard: Used as an analytical standard in quality control laboratories for the identification and quantification of related compounds.

Basic Information

Item	Detail
Product Name	Poly(2-Fluoroadenylic Acid)
CAS No.	71261-44-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2-Fluoroadenylic Acid Polymer; Poly(2-F-AMP); Poly(2-fluoro-AMP); 2-Fluoroadenosine 5'-monophosphate Polymer; Poly(2-fluoroadenosine monophosphate); 2-F-AMP Polymer; Poly(2F-Ado-5'-P)
EINECS	Contact for details

Quality Control

Our Poly(2-Fluoroadenylic Acid) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to current industry standards for fine chemicals and research-grade biochemicals. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing key parameters such as purity, identity, and moisture content. Specifications can be tailored to meet specific research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions or under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Moisture (KF Titration)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.