Description

Deoxyadenylyl-(3'-5')-Deoxycytidylyl-(3'-5')-Deoxyadenosine is a defined oligonucleotide sequence, a trimer composed of deoxyadenosine and deoxycytidine nucleotides. This compound is a critical building block and reference standard in nucleic acid research and therapeutic development. It is primarily utilized by biotechnology and pharmaceutical companies engaged in oligonucleotide synthesis, molecular diagnostics, and the study of genetic mechanisms.

Application

• Oligonucleotide Synthesis: Serves as a key intermediate or reference standard in the solid-phase synthesis of longer DNA strands for research and therapeutic applications.
• Molecular Biology Research: Used as a primer, probe, or model substrate in studies involving DNA replication, PCR, sequencing, and hybridization assays.
• Antisense & Therapeutic Development: Acts as a core sequence component in the development of antisense oligonucleotides and other nucleic acid-based therapeutics.
• Diagnostic Assay Development: Employed in the design and calibration of diagnostic kits for genetic testing and pathogen detection.
• Biochemical Standard: Provides a high-purity standard for analytical method development, validation, and quality control in laboratories.
• Enzymology Studies: Used as a specific substrate to study the activity, kinetics, and inhibition of nucleases, polymerases, and other DNA-modifying enzymes.

Basic Information

Product Name	Deoxyadenylyl-(3'-5')-Deoxycytidylyl-(3'-5')-Deoxyadenosine
CAS No.	70419-16-8
Molecular Formula	C31H39N15O18P2
Molecular Weight	931.67 g/mol
Synonyms	d(ApCpA); d(A-C-A); Deoxyadenylyl-deoxycytidylyl-deoxyadenosine; dA-C-A Trimer; 5'-d(ACA)-3'; Deoxyribonucleotide trimer ACA; Adenine-cytosine-adenine oligonucleotide; d(ACA)
EINECS	Contact for details

Quality Control

Our oligonucleotide products are manufactured under strict quality management systems. Each batch is characterized using advanced analytical techniques including HPLC, MS, and UV spectroscopy to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate at -20°C. Allow the vial to warm to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with molecular structure
Purity (HPLC)	≥ 95% (Area % at 260 nm)
Assay (UV)	≥ 90% (Calculated on dried basis)
Water Content (KF)	≤ 5.0%
Extinction Coefficient (ε260)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.