Description

3-Fluoro-2-Hydroxy-Benzoic Acid Methyl Ester is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a phenolic hydroxyl and an ester group ortho to a fluorine atom, makes it a valuable precursor for creating complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial R&D departments engaged in the development of pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Serves as a core structure in the development of new-generation herbicides, fungicides, and plant growth regulators, where the fluorine atom enhances bioactivity and environmental stability.
• Ligand and Catalyst Development: Used to prepare chelating ligands for metal catalysts in asymmetric synthesis and cross-coupling reactions due to the adjacent oxygen donor atoms.
• Material Science Precursor: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and organic electronic materials where fluorination improves thermal and chemical resistance.
• Chemical Biology Probe: Useful for synthesizing fluorescent tags or molecular probes to study biological processes and enzyme mechanisms.

Basic Information

Product Name	3-Fluoro-2-Hydroxy-Benzoic Acid Methyl Ester
CAS No.	70163-98-3
Molecular Formula	C8H7FO3
Molecular Weight	170.14 g/mol
Synonyms	Methyl 3-Fluoro-2-Hydroxybenzoate; Methyl 3-Fluorosalicylate; 2-Hydroxy-3-Fluorobenzoic Acid Methyl Ester; 3-Fluoro-2-Hydroxy Methyl Benzoate; 3-Fluorosalycylic Acid Methyl Ester; Salicylic Acid, 3-Fluoro-, Methyl Ester; Benzoic acid, 3-fluoro-2-hydroxy-, methyl ester
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Hydroxy-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications in cGMP and ISO-compliant research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.