Description

9,10-Didehydro-1,6-Dimethyl-n-Ethylergoline-8β-Carboxamide is a high-purity ergoline derivative, a key structural motif in numerous pharmacologically active compounds. This compound serves as a critical advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on neuroscience and receptor-targeted drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex ergot alkaloid derivatives and potential active pharmaceutical ingredients (APIs).
• Neurological Research: Used in preclinical studies to investigate interactions with serotonin, dopamine, and adrenergic receptor systems.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new compounds with targeted pharmacological profiles.
• Biochemical Research: Utilized as a tool compound for studying signal transduction pathways and enzyme inhibition.

Basic Information

Item	Details
Product Name	9,10-Didehydro-1,6-Dimethyl-n-Ethylergoline-8β-Carboxamide
CAS No.	7240-57-5
Molecular Formula	C20H25N3O
Molecular Weight	323.44 g/mol
Synonyms	Lisuride Impurity; 9,10-Didehydro-6-methyl-8β-[(methylamino)carbonyl]ergoline-1-ethanol; 1,6-Dimethyl-9,10-didehydroergoline-8β-carboxamide; Lysenyl Impurity; LY-127809 Impurity; (8β)-9,10-Didehydro-1,6-dimethylergoline-8-carboxamide; N-Ethyl-9,10-didehydro-1,6-dimethylergoline-8β-carboxamide
EINECS	Contact for details

Quality Control

Our 9,10-Didehydro-1,6-Dimethyl-n-Ethylergoline-8β-Carboxamide is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC purity analysis and spectroscopic identification, to ensure it meets exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.