Description

Oxacillin Sodium Monohydrate CAS NO 7240-38-2 is a semisynthetic, β-lactamase-resistant penicillin antibiotic in its sodium salt form. This compound is critically important for its targeted efficacy against penicillinase-producing staphylococci, offering a crucial therapeutic option where other penicillins fail. It is primarily required by pharmaceutical manufacturers for the formulation of sterile injectable solutions and active pharmaceutical ingredient (API) production, serving hospitals and clinical settings worldwide.

Application

• Active Pharmaceutical Ingredient (API) in the manufacture of sterile injectable antibiotic formulations.
• Research and development of novel antibiotic combinations and delivery systems.
• Reference standard in analytical laboratories for quality control and method validation.
• Intermediate in the synthesis of more complex antibiotic derivatives.
• Component in microbiological media and diagnostic kits for bacterial resistance testing.
• Use in veterinary medicine for treating specific bacterial infections in animals.

Basic Information

Product Name	Oxacillin Sodium Monohydrate
CAS No.	7240-38-2
Molecular Formula	C19H18N3NaO5S • H2O
Molecular Weight	441.42 g/mol
Synonyms	Oxacillin Sodium Salt Monohydrate; Sodium (2S,5R,6R)-3,3-dimethyl-6-[[(5-methyl-3-phenyl-1,2-oxazole-4-carbonyl)amino]]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate monohydrate; Bactocill; Prostaphlin; 5-Methyl-3-phenyl-4-isoxazolyl penicillin sodium monohydrate; Oxacillin Sodium Hydrate; Isoxazolyl Penicillin Sodium Salt
EINECS	230-636-5

Quality Control

Our Oxacillin Sodium Monohydrate is manufactured and tested to meet stringent pharmaceutical-grade standards, including potential compliance with USP, EP, and BP monographs. Every batch undergoes comprehensive analytical testing for identity, potency, purity, and specific impurities. A detailed Certificate of Analysis (COA) documenting all test results is provided to ensure full traceability and regulatory support for your manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC, anhydrous basis)	95.0% - 102.0%
pH (1% solution)	5.0 - 7.0
Water Content (KF)	3.5% - 5.0%
Specific Optical Rotation	+195° to +210°
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Bacterial Endotoxins	<0.17 IU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.