Description

Mefruside CAS NO 7195-27-9 is a high-purity sulfonamide diuretic compound. It serves as a critical active pharmaceutical ingredient (API) and a valuable reference standard in pharmaceutical research and development. This compound is essential for manufacturers and research institutions focused on cardiovascular and renal therapeutics. Its consistent quality and reliable supply are paramount for ensuring the efficacy and safety of downstream pharmaceutical products.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of diuretic and antihypertensive medications.
• Pharmaceutical Reference Standard for quality control, method validation, and regulatory submissions.
• Biochemical Research for studying renal physiology, sodium-chloride symporter (NCC) inhibition, and fluid balance mechanisms.
• Preclinical and Clinical Studies as a key material for pharmacokinetic and pharmacodynamic investigations.
• Analytical Chemistry for use as a certified standard in HPLC, LC-MS, and other chromatographic assays.

Basic Information

Product Name	Mefruside
CAS No.	7195-27-9
Molecular Formula	C12H16ClNO4S2
Molecular Weight	337.85 g/mol
Synonyms	Mefruside; Baycaron; Mefrusidum; 4-Chloro-N1-methyl-N1-(tetrahydro-2-furanylmethyl)-1,3-benzenedisulfonamide; 4-Chloro-N-methyl-N-[(tetrahydrofuran-2-yl)methyl]-1,3-benzenedisulfonamide; FR-6-103; Mefrusida; Mefrusidum [INN-Latin]
EINECS	Contact for details

Quality Control

Our Mefruside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and IR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your stringent quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.