Description

Sodium [2S-(2Alpha,5Alpha,6Beta)]-6-[(Allylthio)Acetamido]-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate CAS NO 7177-54-0 is a high-purity sodium salt derivative of a penicillin core structure, valued as a critical pharmaceutical intermediate. This compound matters for its role in the synthesis of advanced β-lactam antibiotics, enabling precise chemical modifications to develop new therapeutic agents. It is primarily needed by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in the development and production of novel antibacterial drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel penicillin and cephalosporin-based antibiotics.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new antibacterial compounds.
• API Synthesis: Serves as a precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) targeting resistant bacterial strains.
• Fine Chemical Production: Employed in controlled chemical reactions to introduce specific functional groups into complex β-lactam molecules.
• Bioconjugation Studies: The allylthio moiety can be utilized for further chemical modifications or conjugation in prodrug development.

Basic Information

Product Name	Sodium [2S-(2Alpha,5Alpha,6Beta)]-6-[(Allylthio)Acetamido]-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate
CAS No.	7177-54-0
Molecular Formula	C15H19N2NaO4S2
Molecular Weight	378.43 g/mol
Synonyms	Sodium 6-(Allylthio)acetamidopenicillanate; 6-[(Allylthio)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Sodium Salt; Sodium Penicillinate Allylthioacetamide Derivative; Allylthioacetamido Penicillin Sodium Salt; Sodium 6-APA Allylthioacetamide; (2S,5R,6R)-6-[(Allylthio)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate Sodium Salt
EINECS	Contact for details

Quality Control

Our Sodium [2S-(2Alpha,5Alpha,6Beta)]-6-[(Allylthio)Acetamido]-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, related substances, and residual solvents are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.