Description

Ampicillin CAS NO 7177-48-2 is a broad-spectrum semi-synthetic β-lactam antibiotic belonging to the aminopenicillin class. It is a critical active pharmaceutical ingredient (API) valued for its bactericidal activity against a wide range of Gram-positive and Gram-negative organisms. This compound is essential for pharmaceutical manufacturers producing injectable and oral dosage forms, as well as for research institutions in microbiology and antibiotic development.

Application

• Pharmaceutical API: Primary use as the active ingredient in the formulation of ampicillin capsules, tablets, and powders for oral suspension.
• Sterile Injectable Formulations: Manufacture of ampicillin sodium for intravenous or intramuscular injection.
• Veterinary Medicine: Production of antibiotic treatments for bacterial infections in livestock and companion animals.
• Microbiological Research: Used as a selective agent in cell culture media and for studying bacterial resistance mechanisms.
• Reference Standard: Serves as a high-purity analytical standard for quality control testing in pharmaceutical laboratories.
• Intermediate Synthesis: Acts as a key starting material or intermediate in the synthesis of more complex antibiotic derivatives.

Basic Information

Product Name	Ampicillin
CAS No.	7177-48-2
Molecular Formula	C16H19N3O4S
Molecular Weight	349.41 g/mol
Synonyms	(2S,5R,6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; D-(-)-α-Aminobenzylpenicillin; Ampicillin Trihydrate (common form); Binotal; Penbritin; Amcill; Omnipen; Principen; Ampicil; AB-PC
EINECS	230-525-2

Quality Control

Our Ampicillin is manufactured under strict quality management systems. It is typically tested to meet or exceed relevant pharmacopeial standards such as USP, EP, and BP. Every batch is accompanied by a comprehensive Certificate of Analysis (COA) confirming identity, purity, and microbiological quality. We ensure traceability and batch-to-batch consistency to support your regulatory filings and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (on dried basis)	96.0% - 102.0%
pH (suspension)	3.5 - 6.0
Loss on Drying	≤ 2.0%
Specific Optical Rotation	+280° to +305°
Related Substances (HPLC)	Total impurities ≤ 3.0% Any individual impurity ≤ 1.0%
Residual Solvents	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.2%
Microbiological Enumeration	Complies with EP/USP

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.