Description

Benzylpenicillin is a fundamental β-lactam antibiotic belonging to the penicillin class, widely recognized for its potent bactericidal activity against a broad spectrum of Gram-positive organisms. Its primary value lies in its critical role as an active pharmaceutical ingredient (API) for the formulation of essential injectable and sterile medicinal products. This high-purity compound is indispensable for pharmaceutical manufacturers, research institutions, and veterinary medicine producers requiring a reliable and effective antibiotic base.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of injectable penicillin G formulations for human therapeutic use.
• Veterinary Medicine: Formulation of antibiotic treatments for bacterial infections in livestock and companion animals.
• Research & Development: Serves as a reference standard and key starting material in microbiological research, antibiotic resistance studies, and new drug development.
• Biosynthesis Intermediate: Used as a precursor in the semi-synthetic production of other penicillin derivatives and β-lactam antibiotics.
• Cell Culture Applications: Employed in selective media in biotechnology and pharmaceutical cell culture processes to prevent bacterial contamination.

Basic Information

Product Name	Benzylpenicillin
CAS No.	7005-30-3
Molecular Formula	C16H18N2O4S
Molecular Weight	334.39 g/mol
Synonyms	Penicillin G; Benzyl Penicillin; Penicillin G Potassium (common salt form); (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; Crystapen; Pentids; Pfizerpen; Benzylpenicillinic Acid
EINECS	Contact for details

Quality Control

Our Benzylpenicillin is manufactured and tested under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. Production adheres to current Good Manufacturing Practices (cGMP), and the material is typically characterized against relevant pharmacopeial monographs (e.g., USP, EP, BP). A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing purity, potency, and impurity profiles to guarantee supply reliability and consistent quality for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C) or as specified. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 96.0% (on anhydrous basis)
Water (Karl Fischer)	≤ 1.0%
pH (suspension)	5.0 - 7.5
Specific Optical Rotation	+285° to +310°
Related Substances (HPLC)	Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%
Bacterial Endotoxins	< 0.25 EU/mg (if for injectable use)
Sterility (where applicable)	Passes test

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.