Description

3-[4-(Trifluoromethoxy)Phenyl]Acrylic Acid is a high-value fluorinated aromatic acrylic acid derivative, serving as a versatile and critical building block in advanced organic synthesis. Its molecular structure, featuring both a reactive acrylic acid moiety and a trifluoromethoxy-substituted phenyl ring, makes it indispensable for introducing specific physicochemical properties into target molecules. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting inflammation, central nervous system disorders, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Polymer Modification: Incorporated as a monomer or cross-linking agent to create specialty polymers with enhanced chemical resistance, low surface energy, and specific optical properties.
• Organic Synthesis Reagent: Utilized in various coupling reactions (e.g., Heck reaction) and as a Michael acceptor for constructing complex molecular architectures in medicinal chemistry research.

Basic Information

Product Name	3-[4-(Trifluoromethoxy)Phenyl]Acrylic Acid
CAS No.	783-13-1
Molecular Formula	C10H7F3O3
Molecular Weight	232.16 g/mol
Synonyms	3-[4-(Trifluoromethoxy)phenyl]prop-2-enoic acid; (E)-3-[4-(Trifluoromethoxy)phenyl]acrylic acid; 4-(Trifluoromethoxy)cinnamic acid; 3-(p-Trifluoromethoxyphenyl)acrylic acid; α,β-Unsaturated acid, 3-[4-(trifluoromethoxy)phenyl]-; Trifluoromethoxycinnamic Acid; TFM-CA; p-Trifluoromethoxycinnamic Acid
EINECS	Contact for details

Quality Control

Our production of 3-[4-(Trifluoromethoxy)Phenyl]Acrylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.