Description

2,4-Difluorocinnamic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring a cinnamic acid backbone with fluorine substituents, makes it a critical intermediate for creating compounds with enhanced biological activity and material properties. This product is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and materials science sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used to construct advanced active ingredients for crop protection products, leveraging fluorine's ability to improve metabolic stability and bioavailability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Chemical Research & Development: A versatile starting material for Suzuki-Miyaura and other cross-coupling reactions to create complex, fluorinated aromatic systems.
• Polymer Modification: Incorporated into polymer chains to impart specific properties such as altered solubility, thermal stability, or optical characteristics.
• Fluorine Chemistry Studies: Used in academic and industrial labs to study the effects of fluorine substitution on reaction pathways and molecular properties.

Basic Information

Product Name	2,4-Difluorocinnamic Acid
CAS No.	774-73-2
Molecular Formula	C9H6F2O2
Molecular Weight	184.14 g/mol
Synonyms	(2E)-3-(2,4-Difluorophenyl)prop-2-enoic acid; trans-2,4-Difluorocinnamic acid; (E)-3-(2,4-Difluorophenyl)acrylic acid; 2,4-Difluorocinnameic Acid; β-(2,4-Difluorophenyl)acrylic acid; 3-(2,4-Difluorophenyl)-2-propenoic acid; 2-Propenoic acid, 3-(2,4-difluorophenyl)-, (E)-
EINECS	Contact for details

Quality Control

Our 2,4-Difluorocinnamic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	185 - 190 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.