Description

Hippuryl-Arg CAS NO 744-46-7 is a synthetic peptide derivative widely recognized as a specific chromogenic substrate for the detection and quantification of trypsin-like serine proteases. This compound is critical for biochemical research and diagnostic applications where precise enzyme activity measurement is required. It is primarily utilized by pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic research institutions focused on enzymology and protease function studies.

Application

• Enzyme Activity Assays: Primary substrate for the colorimetric or fluorometric determination of trypsin, thrombin, plasmin, and other related serine proteases.
• Diagnostic Reagent Manufacturing: A key component in the formulation of clinical diagnostic kits for monitoring coagulation disorders and pancreatic function.
• Pharmaceutical Research & Development: Used in high-throughput screening (HTS) to identify and characterize novel protease inhibitors for drug discovery programs.
• Biochemical Research: Essential tool for studying enzyme kinetics, specificity, and inhibition mechanisms in academic and industrial laboratories.
• Quality Control in Biologics: Employed to assess the presence and activity of residual proteases in biopharmaceutical production processes.

Basic Information

Product Name	Hippuryl-Arg
CAS No.	744-46-7
Molecular Formula	C20H29N7O5
Molecular Weight	447.49 g/mol
Synonyms	Hippuryl-L-arginine; N-Benzoylglycyl-L-arginine; Bz-Gly-Arg; Hippurylarginine; Benzoylglycyl-L-arginine; L-Arginine, N2-(N-benzoylglycyl)-; Bz-Gly-Arg-OH; Trypsin Chromogenic Substrate
EINECS	Contact for details

Quality Control

Our Hippuryl-Arg is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and specific optical rotation verification. Certificates of Analysis (COA) detailing all test results are provided to ensure the material meets the stringent requirements for research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to moisture or light should be avoided to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	-15.0° to -18.0° (c=1 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.