Description

Benzoic Acid, 4-(Fluorocarbonyl)-, Methyl Ester (9Ci) is a specialized fluorinated benzoate derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines a reactive fluorocarbonyl group with a stable aromatic ester, enabling precise chemical modifications. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, including protease inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of novel herbicides and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic compounds used in electronic display technologies.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, improving chemical resistance and surface properties.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Stille) for constructing complex biaryl systems.
• Peptide Mimetics & PROTACs: Utilized in medicinal chemistry for constructing linkers and fluorinated analogs in targeted protein degradation platforms.

Basic Information

Product Name	Benzoic Acid, 4-(Fluorocarbonyl)-, Methyl Ester (9Ci)
CAS No.	709-69-3
Molecular Formula	C9H7FO3
Molecular Weight	182.15 g/mol
Synonyms	Methyl 4-(Fluorocarbonyl)benzoate; 4-(Fluorocarbonyl)benzoic Acid Methyl Ester; Methyl 4-Fluorocarbonylbenzoate; 4-Carboxybenzoyl Fluoride Methyl Ester; Terephthalic Acid Monofluoride Methyl Ester; 4-(Methoxycarbonyl)benzoyl Fluoride; 709-69-3; Methyl 4-(fluorocarbonyl)benzoate (9CI)
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4-(Fluorocarbonyl)-, Methyl Ester (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions or an inert atmosphere to prevent hydrolysis. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.