Description

Methyl 5-(Bromomethyl)-2-Fluorobenzoate is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. This compound is valued for its dual functional groups, which allow for versatile derivatization and incorporation into complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the synthesis of fluorinated electron-transport or host materials for improved device efficiency.
• Cross-Coupling Reactions: The bromomethyl moiety makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to construct biaryl systems.
• Polymer Chemistry: Can be utilized as a monomer or modifier to introduce fluorine and reactive sites into specialty polymers for enhanced chemical resistance.

Basic Information

Product Name	Methyl 5-(Bromomethyl)-2-Fluorobenzoate
CAS No.	709-45-5
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	2-Fluoro-5-(bromomethyl)benzoic Acid Methyl Ester; Methyl 2-Fluoro-5-(bromomethyl)benzoate; 5-(Bromomethyl)-2-fluorobenzoic Acid Methyl Ester; Benzoic acid, 5-(bromomethyl)-2-fluoro-, methyl ester; 709-45-5; Methyl 5-bromomethyl-2-fluorobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 5-(Bromomethyl)-2-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures material consistency for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.