Description

Oxiranecarboxylic Acid, 2-(Trifluoromethyl)-, (2S)- (9Ci) is a high-value, chiral building block characterized by its epoxide and trifluoromethyl functionalities. This compound is essential for introducing both stereochemical complexity and the metabolically stable trifluoromethyl group into target molecules, significantly enhancing their biological activity and physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves efficacy and environmental stability.
• Liquid Crystal & Advanced Material Precursor: Serves as a building block for fluorinated monomers and polymers used in electronic displays and specialty coatings.
• Asymmetric Catalysis & Ligand Development: Employed in academic and industrial research for constructing complex molecular architectures and developing new chiral catalysts.
• Fluorine Chemistry Research: A valuable reagent for studying the introduction and effects of fluorine atoms in organic molecules.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for clinical trials and niche market applications.

Basic Information

Item	Detail
Product Name	Oxiranecarboxylic Acid, 2-(Trifluoromethyl)-, (2S)- (9Ci)
CAS No.	693287-30-8
Molecular Formula	C5H3F3O3
Molecular Weight	168.07 g/mol
Synonyms	(2S)-2-(Trifluoromethyl)oxirane-2-carboxylic acid; (S)-2-(Trifluoromethyl)glycidic acid; (S)-3,3,3-Trifluoro-2-oxiranecarboxylic acid; (-)-2-(Trifluoromethyl)glycidic acid; (S)-TFGA; (2S)-2-(Trifluoromethyl)oxiranecarboxylic acid; (S)-Trifluoromethylglycidic Acid
EINECS	Contact for details

Quality Control

Every batch of Oxiranecarboxylic Acid, 2-(Trifluoromethyl)-, (2S)- is produced under strict quality management systems. We guarantee high chiral purity and chemical consistency through advanced analytical techniques including chiral HPLC, 1H/19F NMR, and GC/MS. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment to ensure it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. Due to its hygroscopic nature, the container should be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain product integrity and prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.