Description

Boc-4-Abz-Osu CAS NO 120465-50-1 is a high-purity, protected amino acid derivative widely used as a key building block in peptide synthesis. Its primary value lies in enabling the controlled introduction of the 4-aminobenzoic acid (Abz) moiety into peptide chains while preventing unwanted side reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing novel peptide-based therapeutics, diagnostic probes, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A crucial reagent for the stepwise construction of complex peptides, especially those containing fluorescent or photoreactive 4-aminobenzoic acid tags.
• Bioconjugation and Probe Development: Used to create peptide conjugates for labeling proteins, antibodies, and other biomolecules in diagnostic and imaging applications.
• Pharmaceutical Intermediate: Serves as a key synthetic intermediate in the research and development of active pharmaceutical ingredients (APIs) with peptide backbones.
• Chemical Biology Research: Employed in the synthesis of peptide substrates, inhibitors, and molecular tools for studying enzyme mechanisms and cellular processes.
• Material Science: Can be utilized in the synthesis of specialized peptide-polymer hybrids or surface-modifying agents.

Basic Information

Product Name	Boc-4-Abz-Osu
CAS No.	120465-50-1
Molecular Formula	C₁₆H₁₈N₂O₆
Molecular Weight	334.33 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-4-aminobenzoic acid N-hydroxysuccinimide ester; Boc-4-aminobenzoic acid OS ester; Boc-Abz-OSu; Boc-p-aminobenzoic acid succinimidyl ester; 1-[(4-{[(tert-Butoxy)carbonyl]amino}benzoyl)oxy]-2,5-pyrrolidinedione; N-Boc-4-aminobenzoic acid N-succinimidyl ester; N-Boc-p-aminobenzoic acid N-hydroxysuccinimide ester; Nα-Boc-4-aminobenzoic acid, N-hydroxysuccinimide ester
EINECS	Contact for details

Quality Control

Every batch of Boc-4-Abz-Osu is manufactured under strict quality management protocols. Our products undergo rigorous quality testing, including HPLC for purity and identity verification by NMR and IR spectroscopy, to ensure compliance with industry standards for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or CoA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.