Description

(+)-Dibenzoyl-L-Tartaric Anhydride CAS NO 17637-11-5 is a high-purity chiral resolving agent and a key synthetic intermediate derived from L-tartaric acid. This compound is critically important for the optical resolution of racemic mixtures, particularly in the pharmaceutical industry for the production of enantiomerically pure active pharmaceutical ingredients (APIs). It is essential for manufacturers and R&D laboratories in the pharmaceutical, fine chemical, and agrochemical sectors who require a reliable and high-quality chiral auxiliary for asymmetric synthesis and separation processes.

Application

• Chiral Resolution Agent: Primarily used for the optical resolution of racemic amines, amino alcohols, and other basic pharmaceuticals to obtain single enantiomers.
• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of enantiopure drugs, including cardiovascular and central nervous system (CNS) agents.
• Asymmetric Synthesis: Acts as a chiral catalyst or auxiliary in stereoselective chemical reactions to induce chirality in target molecules.
• Analytical Chemistry: Used in the development of chiral stationary phases (CSPs) for High-Performance Liquid Chromatography (HPLC) to separate enantiomers.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where specific stereochemistry is required.
• Academic & Industrial R&D: A valuable reagent for research in organic chemistry and process development for new chiral entities.

Basic Information

Product Name	(+)-Dibenzoyl-L-Tartaric Anhydride
CAS No.	17637-11-5
Molecular Formula	C18H12O7
Molecular Weight	340.28 g/mol
Synonyms	(+)-O,O'-Dibenzoyl-L-tartaric Anhydride; (2R,3R)-2,3-Bis(benzoyloxy)succinic Anhydride; L-(+)-Dibenzoyltartaric Anhydride; DBTA Anhydride; (2R,3R)-2,3-Di(benzoyloxy)butanedioic Anhydride; Anhydride of L-(+)-Dibenzoyltartaric Acid; (R,R)-Dibenzoyl Tartaric Anhydride
EINECS	Contact for details

Quality Control

Our (+)-Dibenzoyl-L-Tartaric Anhydride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for chiral resolution and pharmaceutical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific rotation is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Specific Rotation [α]20/D	+150° to +160° (c=1 in acetone)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.