Description

Boc-o-Benzyl-L-Serine n-Carboxy Anhydride is a high-purity, protected amino acid derivative specifically engineered for advanced peptide synthesis. This compound is a critical building block for the controlled, racemization-free introduction of serine residues into complex peptide chains, ensuring high coupling efficiency and product integrity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key monomer for the sequential assembly of peptides on resin supports, particularly for incorporating protected serine.
• Solution-Phase Peptide Synthesis: Used in classical coupling strategies for constructing peptide fragments in solution.
• Pharmaceutical R&D: Serves as a crucial intermediate in the research and development of peptide-based drugs, hormones, and vaccines.
• Bioconjugation: Facilitates the site-specific modification of peptides and proteins for drug delivery systems or diagnostic probes.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive peptide leads.
• Academic Research: Used in university and institutional labs for studying peptide structure, function, and synthesis methodologies.

Basic Information

Product Name	Boc-o-Benzyl-L-Serine n-Carboxy Anhydride
CAS No.	125814-31-5
Molecular Formula	C16H19NO6
Molecular Weight	321.33 g/mol
Synonyms	Boc-Ser(Bzl)-NCA; Nα-(tert-Butoxycarbonyl)-O-benzyl-L-serine N-carboxyanhydride; Boc-O-benzyl-L-serine NCA; (4S)-4-[(tert-Butoxycarbonyl)amino]-5-oxo-2-oxazolidinepropanoic acid benzyl ester; NCA-Boc-Ser(Bzl); tert-Butyloxycarbonyl-O-benzyl-L-serine N-carboxyanhydride; Boc-L-Ser(Bzl)-NCA
EINECS	Contact for details

Quality Control

Our Boc-o-Benzyl-L-Serine n-Carboxy Anhydride is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive pharmaceutical research. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Solubility	Soluble in THF, DMF, DCM; slightly soluble in ethyl acetate

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.