Description

Trichloroacetic Anhydride is a highly reactive acylating agent and a key intermediate in organic synthesis. This compound is essential for introducing the trichloroacetyl group, enabling the production of pharmaceuticals, agrochemicals, and specialty polymers. It is primarily utilized by research institutions and industrial manufacturers in the fine chemical, pharmaceutical, and material science sectors.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring the trichloroacetyl protecting group.
• Agrochemical Production: Serves as a building block for manufacturing herbicides, fungicides, and other crop protection agents.
• Polymer Chemistry: Acts as a monomer or modifier in the production of specialty polymers and resins with enhanced properties.
• Organic Synthesis Reagent: A versatile reagent for acylation reactions in laboratory-scale and pilot-scale organic synthesis.
• Dye and Pigment Manufacturing: Employed in the synthesis of complex organic dyes and pigments.
• Peptide Synthesis: Can be used for the protection of amino groups during peptide coupling processes.

Basic Information

Product Name	Trichloroacetic Anhydride
CAS No.	4124-31-6
Molecular Formula	C4Cl6O3
Molecular Weight	286.76 g/mol
Synonyms	Trichloroacetic Acid Anhydride; Acetyl Trichloride, Anhydride; Perchloroacetic Anhydride; Hexachloroacetic Anhydride; Bis(trichloroacetyl) Ether; Trichloroacetyl Anhydride; TCAA
EINECS	223-927-5

Quality Control

Our Trichloroacetic Anhydride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the rigorous standards required for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, amines, and alcohols. Due to its nature as a strong acid/organic solvent, ensure containers are kept tightly sealed to prevent moisture absorption and decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Trichloroacetic Acid	≤ 1.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.