Description

6-Amino-2-Chloro-3-Fluorobenzoic Acid is a high-purity, multi-functional benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its unique trifunctional structure, featuring amino, chloro, and fluoro substituents, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing complex dyes and pigments with specific color fastness and light-absorbing properties.
• Custom Synthesis and Contract Manufacturing: A valuable substrate for custom chemical synthesis services and scale-up projects in fine chemical production.

Basic Information

Product Name	6-Amino-2-Chloro-3-Fluorobenzoic Acid
CAS No.	681459-97-2
Molecular Formula	C7H5ClFNO2
Molecular Weight	189.57 g/mol
Synonyms	2-Chloro-3-fluoro-6-aminobenzoic acid; 3-Fluoro-2-chloro-6-aminobenzoic acid; 6-Amino-2-chloro-3-fluorobenzoic acid; Benzoic acid, 6-amino-2-chloro-3-fluoro-; 681459-97-2; 2-Chloro-3-fluoro-6-aminobenzoic acid; 3-Fluoro-2-chloro-6-aminobenzoic acid
EINECS	Contact for details

Quality Control

Our 6-Amino-2-Chloro-3-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.