Description

Benzenepropanoic Acid, 2,4-Difluoro--α--Oxo- (9Ci) is a high-purity fluorinated aromatic building block, identified by CAS No. 676530-01-1. This compound is valued for its role as a key synthetic intermediate in advanced organic synthesis, enabling the introduction of a reactive keto-acid moiety onto a difluorobenzene scaffold. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex, bioactive molecules.

Application

• Pharmaceutical intermediate for the synthesis of active pharmaceutical ingredients (APIs) with fluorinated aromatic systems.
• Key building block in medicinal chemistry research for creating novel drug candidates, particularly in kinase inhibitor and anti-inflammatory agent development.
• Precursor for advanced agrochemicals, including herbicides and fungicides, where the difluoro substitution pattern enhances biological activity and stability.
• Starting material for the preparation of specialized ligands and catalysts used in asymmetric synthesis.
• Intermediate in the production of dyes, pigments, and advanced materials requiring specific fluorinated aromatic components.
• Used in academic and industrial R&D for exploring structure-activity relationships (SAR) in fluoroorganic chemistry.

Basic Information

Product Name	Benzenepropanoic Acid, 2,4-Difluoro--α--Oxo- (9Ci)
CAS No.	676530-01-1
Molecular Formula	C9H6F2O3
Molecular Weight	200.14 g/mol
Synonyms	2,4-Difluoro-α-oxobenzenepropanoic Acid; 3-(2,4-Difluorophenyl)-3-oxopropanoic Acid; 2,4-Difluorobenzoylacetic Acid; 3-Oxo-3-(2,4-difluorophenyl)propanoic Acid; (2,4-Difluorobenzoyl)acetic Acid; DFBAA; 676530-01-1 (CAS)
EINECS	Contact for details

Quality Control

Our Benzenepropanoic Acid, 2,4-Difluoro--α--Oxo- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.