Description

2-Biphenyl-3'-Fluoro-Acetic Acid is a high-purity fluorinated biphenyl acetic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atom and the biphenyl-acetic acid scaffold, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine-tuning material properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting neurological and inflammatory pathways.
• Agrochemical Research: Used in developing new-generation herbicides and fungicides, where the fluorine atom enhances bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structure for synthesizing fluorinated organic semiconductors and liquid crystal molecules for electronic displays.
• Ligand & Catalyst Development: Employed in creating specialized ligands for transition metal catalysis and asymmetric synthesis.
• Polymer Modification: Acts as a monomer or functionalizing agent to introduce fluorinated biphenyl groups into polymer chains, altering thermal and optical properties.
• Academic & R&D: A valuable reagent for medicinal chemistry and material science research in academic and corporate laboratories.

Basic Information

Product Name	2-Biphenyl-3'-Fluoro-Acetic Acid
CAS No.	669713-85-3
Molecular Formula	C14H11FO2
Molecular Weight	230.24 g/mol
Synonyms	3'-Fluoro-[1,1'-biphenyl]-2-acetic Acid; 2-(3-Fluorobiphenyl-2-yl)acetic Acid; [1,1'-Biphenyl]-2-acetic Acid, 3'-Fluoro-; 3-Fluoro-2-biphenylacetic Acid; 2-Biphenyl-3'-fluoroacetic Acid; Biphenyl-3'-fluoro-acetic acid; (3'-Fluoro[1,1'-biphenyl]-2-yl)acetic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Biphenyl-3'-Fluoro-Acetic Acid is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Individual unknown impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.