Description

Tetrahydrogalantamine is a synthetic derivative of the natural alkaloid galantamine, representing a key intermediate in advanced pharmaceutical synthesis. This compound is valued for its role in developing novel acetylcholinesterase inhibitors and other bioactive molecules targeting the central nervous system. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of treatments for neurological conditions and cognitive disorders.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced galantamine analogs and related therapeutic agents.
• Neurological Research: Used in preclinical studies to investigate mechanisms related to acetylcholinesterase inhibition and cognitive enhancement.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the manufacturing process for potential new chemical entities (NCEs).
• Biochemical Assays: Employed as a reference standard or reagent in high-throughput screening and pharmacological testing.
• Academic & Contract Research: Utilized in university and CRO laboratories for synthetic organic chemistry and medicinal chemistry projects.

Basic Information

Product Name	Tetrahydrogalantamine
CAS No.	664995-65-7
Molecular Formula	C17H23NO3
Molecular Weight	289.37 g/mol
Synonyms	Narwedine, Dihydrogalantamine; Tetrahydrogalanthamine; 4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol; Galantamine Impurity; Galanthamine Tetrahydro Derivative
EINECS	Contact for details

Quality Control

Our Tetrahydrogalantamine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.