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5-Amino-4-Fluoro-2-Methyl-Benzoic Acid CAS NO 658085-42-8


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CAS No.:658085-42-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Amino-4-Fluoro-2-Methyl-Benzoic Acid is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. Its unique substitution pattern, featuring both an amino and a carboxylic acid group on a fluorinated benzene ring, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting various therapeutic areas.
  • Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and stability.
  • Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic components in electronic display materials and organic light-emitting diodes (OLEDs).
  • Dye & Pigment Manufacturing: Employed in the synthesis of specialized, high-performance dyes and pigments due to its amino and carboxylic acid functional groups.
  • Polymer Modification: Acts as a monomer or modifier to introduce fluorine and reactive sites into polymer chains, enhancing material properties like chemical resistance.
  • Chemical Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and material science for structure-activity relationship (SAR) studies.

Basic Information

Product Name 5-Amino-4-Fluoro-2-Methyl-Benzoic Acid
CAS No. 658085-42-8
Molecular Formula C8H8FNO2
Molecular Weight 169.15 g/mol
Synonyms 4-Fluoro-5-amino-2-methylbenzoic acid; 2-Methyl-5-amino-4-fluorobenzoic acid; 5-Amino-4-fluoro-o-toluic acid; Benzoic acid, 5-amino-4-fluoro-2-methyl-; 658085-42-8; 4-Fluoro-2-methyl-5-aminobenzoic acid; 5-Amino-4-fluoro-2-methylbenzoate
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Quality Control

Our 5-Amino-4-Fluoro-2-Methyl-Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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