Description

2-Bromo-4,6-Difluorobenzoic Acid is a high-purity halogenated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of bromine and fluorine atoms on the aromatic ring, which enables precise structural modifications and the introduction of unique electronic properties into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluoro and bromo substituents contribute to biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a foundational component in the synthesis of fluorinated organic electronic materials for displays and lighting technologies.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille) to construct complex biaryl systems.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands and organocatalysts for asymmetric synthesis and other catalytic processes.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2-Bromo-4,6-Difluorobenzoic Acid
CAS No.	651026-99-2
Molecular Formula	C7H3BrF2O2
Molecular Weight	236.99 g/mol
Synonyms	Benzoic acid, 2-bromo-4,6-difluoro-; 4,6-Difluoro-2-bromobenzoic acid; 2-Bromo-4,6-difluorobenzoic acid; 651026-99-2; AI3-32872; AKOS015903991; BRN 2965435; CS-W009767; FT-0658847; SCHEMBL155062; ZINC000257049509
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4,6-Difluorobenzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity requirements for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant techniques is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.