Description

4-Methoxy-3-(trifluoromethoxy)benzoic acid, 97% is a high-purity fluorinated benzoic acid derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both methoxy and trifluoromethoxy substituents, provides valuable electronic and steric properties for modifying molecular characteristics. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic components in electronic materials, contributing to the tuning of dielectric anisotropy and charge transport properties.
• Polymer Modification: Acts as a monomer or functionalization agent for creating specialty polymers with specific thermal, chemical, or surface properties.
• Chemical Research & Development: Employed as a standard or reagent in method development and catalysis studies within academic and industrial R&D laboratories.
• Fluorine Chemistry Building Block: A valuable starting material for further functionalization and the introduction of complex fluorinated motifs into target molecules.

Basic Information

Item	Details
Product Name	4-Methoxy-3-(trifluoromethoxy)benzoic acid, 97%
CAS No.	647855-22-9
Molecular Formula	C9H7F3O4
Molecular Weight	236.15 g/mol
Synonyms	3-(Trifluoromethoxy)-4-methoxybenzoic acid; 4-Methoxy-3-trifluoromethoxybenzoic acid; Benzoic acid, 4-methoxy-3-(trifluoromethoxy)-; 647855-22-9; 4-Methoxy-α,α,α-trifluoro-m-anisic acid
EINECS	Contact for details

Quality Control

Our 4-Methoxy-3-(trifluoromethoxy)benzoic acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency meet the specified 97% minimum assay. A detailed Certificate of Analysis (COA) documenting all test results is provided with each shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.