Description

5-(3,5-Bis(Trifluoromethylphenyl)-Furan-2-Carboxylic Acid is a high-value fluorinated organic building block, prized for its unique trifluoromethylphenyl and furan-carboxylic acid functional groups. This compound is essential for introducing lipophilicity, metabolic stability, and electronic effects into advanced molecular architectures. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology, central nervous system (CNS), and anti-inflammatory therapies.
• Agrochemical Synthesis: Used to construct advanced active ingredients for crop protection, leveraging the trifluoromethyl group to enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its conjugated furan ring and fluorine content.
• Chemical Biology Probes: Employed in the design of fluorinated probes and inhibitors for studying enzyme mechanisms and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	5-(3,5-Bis(Trifluoromethylphenyl)-Furan-2-Carboxylic Acid
CAS No.	638159-97-4
Molecular Formula	C14H5F6O3
Molecular Weight	350.18 g/mol
Synonyms	5-[3,5-Bis(trifluoromethyl)phenyl]-2-furancarboxylic acid; 5-(3,5-Bis(trifluoromethyl)phenyl)furan-2-carboxylic acid; 2-Furancarboxylic acid, 5-[3,5-bis(trifluoromethyl)phenyl]-; 638159-97-4; 5-(3,5-Bis(trifluoromethyl)phenyl)-2-furoic acid
EINECS	Contact for details

Quality Control

Every batch of 5-(3,5-Bis(Trifluoromethylphenyl)-Furan-2-Carboxylic Acid is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for research and process development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.