Description

1-(3,5-Difluorophenyl)Cyclopentane-1-Carboxylic Acid is a high-purity fluorinated organic building block of significant synthetic utility. This compound is valued for its role as a key intermediate in the development of advanced pharmaceutical and agrochemical agents. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules with tailored biological and physical properties.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the difluorophenyl moiety can enhance metabolic stability and bioavailability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the research of specialty polymers and liquid crystals, where fluorinated aromatic systems impart unique thermal and chemical resistance.
• Chemical Biology & Proteomics: Utilized as a scaffold for designing molecular probes and enzyme inhibitors in biochemical research.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	1-(3,5-Difluorophenyl)Cyclopentane-1-Carboxylic Acid
CAS No.	610791-42-9
Molecular Formula	C12H12F2O2
Molecular Weight	226.22 g/mol
Synonyms	1-(3,5-Difluorophenyl)cyclopentanecarboxylic acid; Cyclopentanecarboxylic acid, 1-(3,5-difluorophenyl)-; 3,5-Difluoro-α,α-cyclopentylbenzenecetic acid; 1-(3,5-Difluorophenyl)-1-cyclopentanecarboxylic acid; α-(3,5-Difluorophenyl)cyclopentanecarboxylic acid; 610791-42-9; 1-Cyclopentyl-3,5-difluorobenzoic acid (common name variant).
EINECS	Contact for details

Quality Control

Our production of 1-(3,5-Difluorophenyl)Cyclopentane-1-Carboxylic Acid adheres to stringent internal quality standards, ensuring batch-to-batch consistency for research and development. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR, MS) to confirm identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development under quality frameworks including cGMP and ISO 9001 for advanced projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.