Description

Methyl 2-(Aminomethyl)-5-Fluorobenzoate Hydrochloride is a high-purity, pharmaceutically relevant organic salt. This compound serves as a critical building block (API intermediate) in the synthesis of complex drug molecules, particularly those targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the production of active pharmaceutical ingredients (APIs), especially for neurological and psychiatric drugs.
• Organic Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Research & Development: Essential reagent in academic and industrial R&D for exploring novel fluorinated benzamide derivatives.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.
• Process Chemistry: Employed in scale-up and process development for the commercial manufacturing of target molecules.

Basic Information

Item	Detail
Product Name	Methyl 2-(Aminomethyl)-5-Fluorobenzoate Hydrochloride
CAS No.	606080-44-8
Molecular Formula	C9H11FNO2 • HCl
Molecular Weight	219.65 g/mol (Free base: 183.19 g/mol)
Synonyms	5-Fluoro-2-(aminomethyl)benzoic acid methyl ester hydrochloride; Methyl 5-fluoro-2-(aminomethyl)benzoate hydrochloride; 2-(Aminomethyl)-5-fluorobenzoic acid methyl ester HCl; 606080-44-8; Benzoic acid, 2-(aminomethyl)-5-fluoro-, methyl ester, hydrochloride; Methyl 2-(aminomethyl)-5-fluorobenzoate HCl
EINECS	Contact for details

Quality Control

Our Methyl 2-(Aminomethyl)-5-Fluorobenzoate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets stringent specifications for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.