Description

Methyl 2-Cyano-5-Fluorobenzoate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. Its core value lies in its bifunctional molecular structure, incorporating both a reactive cyano group and a fluorinated aromatic ring, enabling precise molecular modifications. This compound is critically needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, particularly in creating complex molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), including kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom enhances lipophilicity and target binding.
• Liquid Crystal Material Precursor: Serves as a starting material for synthesizing fluorinated liquid crystals used in advanced display technologies.
• Organic Electronics: Employed in the development of novel organic semiconductors and electron-transport materials due to its electron-withdrawing cyano and fluoro groups.
• Chemical Research & Development: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to construct complex biaryl systems.
• Fluorine Chemistry Studies: Used as a model compound in academic and industrial research to study the effects of fluorine substitution on aromatic systems.

Basic Information

Product Name	Methyl 2-Cyano-5-Fluorobenzoate
CAS No.	606080-43-7
Molecular Formula	C9H6FNO2
Molecular Weight	179.15 g/mol
Synonyms	Methyl 5-Fluoro-2-cyanobenzoate; 5-Fluoro-2-cyanobenzoic Acid Methyl Ester; 2-Cyano-5-fluorobenzoic Acid Methyl Ester; Benzoic acid, 2-cyano-5-fluoro-, methyl ester; Methyl 5-fluoro-2-cyanobenzoate; Methyl 2-cyano-5-fluorobenzoate; 606080-43-7; Methyl 5-fluoro-2-cyanobenzenecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 2-Cyano-5-Fluorobenzoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC/GC purity data and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (Area Percent)
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.