Description

8-Deoxyrifamycin W is a key semi-synthetic derivative and a crucial intermediate in the synthesis of advanced rifamycin antibiotics. This compound matters for its role in developing potent antimicrobial agents targeting resistant bacterial strains. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in antibiotic discovery and development programs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of next-generation rifamycin-class antibiotics.
• Antimicrobial Research: Used in biochemical and microbiological studies to investigate structure-activity relationships (SAR) against Mycobacterium tuberculosis and other pathogens.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of specialized rifamycin analogs with modified pharmacological properties.
• Reference Standard: Employed as an analytical standard in quality control laboratories for the identification and quantification of related compounds.
• Academic & Contract Research: Utilized in university and CRO settings for fundamental research on bacterial RNA polymerase inhibition.

Basic Information

Product Name	8-Deoxyrifamycin W
CAS No.	69239-55-0
Molecular Formula	C38H47NO12
Molecular Weight	709.78 g/mol
Synonyms	8-Deoxy-rifamycin W; Rifamycin W, 8-deoxy-; (12Z,14E,24E)-(2S,12S,16S,17S,18R,19R,20R,21S,22R,23S)-21-(Acetyloxy)-6,9,17,19-tetrahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-5-yl acetate; 8-Deoxy-rifamycin; Antibiotic X 127
EINECS	Contact for details

Quality Control

Our 8-Deoxyrifamycin W is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.